FMRI

Systematic evaluation of fMRI data-processing pipelines for consistent functional connectomics

We benchmarked >750 data-processing pipelines to construct a functional connectivity network from fMRI data.

Jun 4, 2024

Local orchestration of distributed functional patterns supporting loss and restoration of consciousness in the primate brain

We show that anaesthesia collapses the principal gradient of macaque functional connectivity, which is restored upon re-awakening induced by thalamic deep-brain stimulation.

Mar 11, 2024

A synergistic workspace for human consciousness revealed by Integrated Information Decomposition

We identify a core of high-synergy regions whose ability to integrate information is compromised during anaesthesia and in patients with disorders of consciousness.

Jul 18, 2023

In vivo mapping of pharmacologically induced functional reorganization onto the human brain’s neurotransmitter landscape

We map changes in brain function induced by 10 anaesthetics, psychedelics,a nd cognitive enhancers onto the comprehensive database of human neurotransmitter receptors from Positron Emission Tomography.

Jun 14, 2023

A synergistic core for human brain evolution and cognition

We show that the human brain relies on synergistic interactions between regions to integrate information and support complex cognition, surpassing the brains of other species and correlating with evolutionary cortical expansion.

May 26, 2022

Dopaminergic brainstem disconnection is common to pharmacological and pathological consciousness perturbation

Anaesthesia and disorders of consciousness share disconnection between the default mode network and dopaminergic ventral tegmental area.

Jul 23, 2021

Consciousness-specific dynamic interactions of brain integration and functional diversity

We compare fMRI brain dynamics during anaesthesia and in patients with disorders of consciousness to identify consistent signatures of consciousness.

Oct 10, 2019