We use computational whole-brain modelling across human, macaque, and mouse to show that models with competitive interactions are more realistic, more personalised, more synergistic, and perform better.
Mar 11, 2026
Across human, macaque, marmoset, and mouse, anaesthesia disrupts integration of information in the mammalian brain, which is restored upon re-awakening by central-thalamic deep-brain stimulation, and reproduced in species-specific computational models.
Jan 28, 2026
Exhaustive decomposition of information into synergistic, redundant, and unique components.
Sep 22, 2025
We compare of >200 measures of pairwise interaction for fMRI functional connectivity.
Jun 6, 2025
Led by Zhen-Qi Liu, comparison of >200 measures of pairwise interaction for fMRI functional connectivity.
May 1, 2025
We review how fundamental building blocks of brain function can be identified through the lenses of space, time, and information. Each lens reveals similarities and differences across anaesthesia, coma, and psychedelics, in humans and across different species.
Jul 1, 2024
Toolbox to decompose information into synergistic, redundant, and unique contributions. By Pedro Mediano.
Jun 26, 2024
We review how disentangling synergistic and redundant information provides a guiding principle for understanding the informational architecture of the brain and cognition and their evolution.
Apr 1, 2024
We identify a core of high-synergy regions whose ability to integrate information is compromised during anaesthesia and in patients with disorders of consciousness.
Jul 18, 2023
We show that the human brain relies on synergistic interactions between regions to integrate information and support complex cognition, surpassing the brains of other species and correlating with evolutionary cortical expansion.
May 26, 2022